Breakouts
Good evidenceDecades of use, FDA-recognized, moderate trial base
Salicylic acid 0.5–2% is an FDA OTC-monograph acne ingredient — a regulatory recognition of efficacy — and controlled trials show reduced comedones and mild-to-moderate breakouts over 8–12 weeks. Head-to-head, it's gentler but somewhat weaker than benzoyl peroxide for inflamed acne.