Dryness
Good evidenceProven hydrator and barrier-recovery aid
Controlled studies show panthenol improves hydration and speeds barrier recovery after irritation (measured as reduced water loss). A dependable supporting ingredient, especially alongside strong actives like retinoids and acids.
The receipts
8 trials/reviews indexed · showing most cited- Randomized trialJ Dermatolog Treat· 2002· cited 61×
Dexpanthenol enhances skin barrier repair and reduces inflammation after sodium lauryl sulphate-induced irritation.
- Randomized trialArzneimittelforschung· 2000· cited 44×
Effect of topically applied dexpanthenol on epidermal barrier function and stratum corneum hydration. Results of a human in vivo study.
- Randomized trialJ Dermatolog Treat· 2017· cited 28×
A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora.
- Randomized trialJ Cosmet Dermatol· 2019· cited 19×
Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial.
- Randomized trialAuris Nasus Larynx· 2020· cited 8×
Randomised trial on performance, safety and clinical benefit of hyaluronic acid, hyaluronic acid plus dexpanthenol and isotonic saline nasal sprays in patients suffering from dry nose symptoms.
- Randomized trialJ Cosmet Dermatol· 2025· cited 3×
Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study.